Sedan vehicles can travel on all the roads that form part of this route.
Four-wheel drive with low range transfer case is only required if you choose to explore the Baviaans Kloof, or Bedrogberg 4x4 Trail in the northern section of Addo NP.
Higher vehicles (such minibus transporters or 4x4 SUV's) are better for game viewing in Addo. In private reserves such as Kariega and Shamwari all game viewing is conducted in all-terrain open game viewing vehicles.
Always take additional water with you in the car. You might just want to take a short hike into a forest or spend some time on a secluded beach.
Check spare tyre and tyre repair equipment

Along the Garden Route there are an abundance of restaurants, shops, grocery stores and accommodation.
Fuel is available along the route.
A wide selection of food is available in all the major towns along the way. This will be for travel days and snacks along the way.
Water is clean and drinkable throughout the route

Always have drinking water available as temperatures can sore during summer.
Use sun-screen and eye protection against the sun, especially when spending time on the beaches and outdoors.
There are large predators in the national parks and reserves (Sanbona, Kariega, Addo and Shamwari). Always obey the rules of the parks and never leave your vehicle if not in a safe, designated place while traveling in the game reserves.
The Knysna forest is ideal for a day hike. Have a daypack and hiking boots/trainers available, and carry enough water and snacks for the walks.
Be aware of your surroundings in cities and towns. It's best to keep your car doors lock.

This route is a very family-orientated accommodated self drive holiday that offers activities for families with children. Children will have lots to learn about the wide variety of interesting places visited along the way. Many child-friendly lodges and accommodation are available to cater for children with lots to do and experience for young and old. Interesting family activities can be enjoyed along the way. Some of the wildlife experiences at places like Shamwari, Sanbona and Kariega includes animal behaviour, spoor identification and track moulds, child-focussed rangers, cooking, wildlife movies, child-minder services, interpretive centres, kiddies menus and play facilities. Addo Main Camp has interesting facilities available for children with a jungle gym in the shape of an elephant as well as lots os space to walk and play.